{"id":705,"date":"2025-06-04T19:18:42","date_gmt":"2025-06-04T11:18:42","guid":{"rendered":"https:\/\/mrc.som.nycu.edu.tw\/?page_id=705"},"modified":"2026-03-07T00:20:27","modified_gmt":"2026-03-06T16:20:27","slug":"%e7%a2%a9%e5%8d%9a%e5%a3%ab%e7%94%9f","status":"publish","type":"page","link":"https:\/\/mrc.som.nycu.edu.tw\/eng\/%e7%a2%a9%e5%8d%9a%e5%a3%ab%e7%94%9f\/","title":{"rendered":"MASTER\u2019S AND PHD STUDENTS"},"content":{"rendered":"\n

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<\/strong><\/p><\/td><\/tr>

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\u7814\u7a76\u767c\u8868\uff1a<\/strong>
Kuo CH<\/strong>, \u2026 Wu CY. Direct effects of alcohol on gut-epithelial barrier: Unraveling the disruption of physical and chemical barrier of the gut-epithelial barrier that compromises the host-microbiota interface upon alcohol exposure. J Gastroenterol Hepatol. 2024;39(7):1247-1255.<\/td><\/tr>
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\u694a\u8ed2\u9298<\/strong>
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\u7814\u7a76\u9818\u57df<\/strong>\uff1a
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\u7814\u7a76\u767c\u8868\uff1a<\/strong><\/strong><\/p><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

\u9ad8\u6b63\u5f65\u8001\u5e2b\u5718\u968a<\/strong><\/h4>\n\n\n\n
\"Jazon

Jazon Harl Hidrosollo<\/strong>
\u535a\u58eb\u751f<\/strong><\/p><\/td>

\u5b78\u6b77\uff1a<\/strong>
Ms., Department of Medical Technology, University of San Agustin, Philippines

\u7814\u7a76\u9818\u57df<\/strong>\uff1a
The mechanism of compound 4e against S. lugdunensis<\/em>

Investigating the mechanism of compound 4e derivatives against S. lugdunensis <\/em>and the mechanism of drug resistance

Association between genotypes and virulence of SL (side project)

The interaction between urinary stones and microbiota (side project)

\u7814\u7a76\u767c\u8868\uff1a<\/strong>
<\/td><\/tr>
\"\u5f35\u664f\u84c1\u535a\u58eb\u751f\"

\u5f35\u664f\u84c1<\/strong>
\u535a\u58eb\u751f<\/strong><\/p><\/td>

\u5b78\u6b77\uff1a<\/strong>
Bs., Department of Biotechnology and Laboratory Science in medicine, National Yang-Ming University, Taiwan

Ms., Institute of Microbiology and Immunology, National Yang Ming Chiao Tung University, Taiwan

\u7814\u7a76\u9818\u57df<\/strong>\uff1a
Investigating the evolutionary mechanisms of strains in patients with recurrent urinary tract infections

Exploring the characteristics of bacteria causing systemic infections 

Characteristics and diagnosis of carbapenemase-producing bacteria (side project)

Investigation of the correlation between microbiota and diseases (side project)

\u7814\u7a76\u767c\u8868\uff1a<\/strong>
<\/td><\/tr>
\"\u90ed\u6c9b\u6600\u535a\u58eb\u751f\"
\u90ed\u6c9b\u6600
\u535a\u58eb\u751f<\/strong><\/td>		\u5b78\u6b77\uff1a<\/strong>
Bs., Department of Biotechnology and Laboratory Science in medicine, Chang-Gung University, Taiwan

Ms., Institute of Microbiology and Immunology, National Yang Ming Chiao Tung University, Taiwan

\u7814\u7a76\u9818\u57df<\/strong>\uff1a
Investigating the roles and interactions of Jhp0417 and Jhp0106 
Exploring the regulatory mechanisms of CsrA 
Investigating the influence of strain-specific regulation of CsrA variants on bacterial virulence
Developing novel probiotics for pets (side project)

\u7814\u7a76\u767c\u8868\uff1a<\/strong>
<\/td><\/tr>
\"Tran

Tran Thi Dieu Thuy<\/strong>
\u535a\u58eb\u751f<\/strong><\/p><\/td>

\u5b78\u6b77\uff1a<\/strong>
Bs., Department of biotechnology, Ton Duc Thang University, Vietnam

Ms., Institute of Microbiology and Immunology, National Yang Ming Chiao Tung University, Taiwan

\u7814\u7a76\u9818\u57df<\/strong>\uff1a
Development and mechanism exploration of traditional probiotic products against pathogenic bacteria

Development of next-generation probiotics for anti-aging effects 

Investigation of the correlation between microbiota and male reproductive tract diseases  
(side project)

\u7814\u7a76\u767c\u8868\uff1a<\/strong>
<\/td><\/tr>
\"Tran

Tran Thi Thuy Duong
\u535a\u58eb\u751f<\/strong><\/p><\/td>

\u5b78\u6b77\uff1a<\/strong>
Bs., Department of biotechnology, Ton Duc Thang University, Vietnam

Ms., Institute of Microbiology and Immunology, National Yang Ming Chiao Tung University, Taiwan

\u7814\u7a76\u9818\u57df<\/strong>\uff1a
Investigating the characteristics of CRhvKP and developing a screening platform

Exploring the evolution and characteristics of CRhvKP, hvKP, and LAhvKP plasmids

Developing bacteriophages to inhibit CRhvKP

Investigating the role of novel virulence factors in the pathogenesis of CRKP 
Studying the evolution of hvKP within the host

Developing antibacterial compounds and analyzing their mechanisms (side project)

\u7814\u7a76\u767c\u8868\uff1a<\/strong>
<\/td><\/tr>
\"Carl Jay

Carl Jay Ballena Bregente<\/strong>
\u535a\u58eb\u751f<\/strong><\/p><\/td>

\u5b78\u6b77\uff1a<\/strong>
Ms., Blizard Institute, London, United Kingdom

\u7814\u7a76\u9818\u57df<\/strong>\uff1a
Investigating the characteristics of carbapenem-resistant (CAZ-AVI\/cefiderocol\/colistin-resistant) Pseudomonas aeruginosa

Exploring the characteristics of hypervirulent and carbapenem-resistant Pseudomonas aeruginosa (HvCRPA)

Development of bacteriophages to combat HvCRPA
Development of bacteriophages to combat carbapenem-resistant Enterobacter cloacae (side project)

Investigation of the correlation between microbiota and male reproductive tract diseases (side project)

\u7814\u7a76\u767c\u8868\uff1a<\/strong>
<\/td><\/tr>
\"\u66fe\u7423\u6dc7\u535a\u58eb\u751f\"

\u66fe\u7423\u6dc7<\/strong>
\u535a\u58eb\u751f<\/strong><\/p><\/td>

\u5b78\u6b77\uff1a<\/strong>
Bs., Universiti Tunku Abdul Rahman, Malaysia

\u7814\u7a76\u9818\u57df<\/strong>\uff1a
Analysis of the characteristics and mechanisms of hypervirulent extensively drug-resistant Acinetobacter baumannii

Analysis of novel mechanisms of carbapenem resistance in Acinetobacter baumannii

Development of bacteriophages to combat hypervirulent XDR Acinetobacter baumannii

Analysis of the impact and mechanisms of induced resistance in Acinetobacter baumannii on pathogenicity

Development of probiotics with the potential to inhibit rUTI (side project)

\u7814\u7a76\u767c\u8868\uff1a<\/strong>
<\/td><\/tr>
\"\u675c\u4f69\u7d14\u535a\u58eb\u751f\"

\u675c\u4f69\u7d14<\/strong>
\u535a\u58eb\u751f<\/strong><\/p><\/td>

\u5b78\u6b77\uff1a<\/strong>
Bs., Department of Food Science and Biotechnology, Chung Hsing University, Taiwan

\u7814\u7a76\u9818\u57df<\/strong>\uff1a
Development and mechanistic study of Next-Generation Probiotics against metabolic syndrome

\u7814\u7a76\u767c\u8868\uff1a<\/strong>
<\/td><\/tr>
\"\u912d\u96c5\u88d5\u535a\u58eb\u751f\"

\u912d\u96c5\u88d5<\/strong>
\u535a\u58eb\u751f<\/strong><\/p><\/td>

\u5b78\u6b77\uff1a<\/strong>
Bs., Department of Life Science, National Tsing Hua University, Taiwan

\u7814\u7a76\u9818\u57df<\/strong>\uff1a
The bacterial interactions in polymicrobial infections and their impact on bacterial pathogenesis

\u7814\u7a76\u767c\u8868\uff1a<\/strong>
<\/td><\/tr>
\"Nevia

Nevia Longjam<\/strong>
\u535a\u58eb\u751f<\/strong><\/p><\/td>

\u5b78\u6b77\uff1a<\/strong>
B.Sc Biotechnology: Chandigarh University, India

M.Sc Biotechnology : Bharathiar University India

\u7814\u7a76\u9818\u57df<\/strong>\uff1a
Investigation the role of Jhp0550 and carbon storage regulator system (Csr) in J99 Helicobacter pylori pathogenesis

Characterization of the virulence phenotypes and its association with genetic profiles in Staphylococcus lugdunensis clinical isolates

\u7814\u7a76\u767c\u8868\uff1a<\/strong>
<\/td><\/tr>
\"Tong

Tong Dang Khoa<\/strong>
\u78a9\u58eb\u751f<\/strong><\/p><\/td>

\u5b78\u6b77\uff1a<\/strong>
Bs., Ho Chi Minh City International University, Vietnam

\u7814\u7a76\u9818\u57df<\/strong>\uff1a
Investigating the characteristics of siderophore-carbapenemase carrying plasmids and their impact on bacterial pathogenesis

\u7814\u7a76\u767c\u8868\uff1a<\/strong>
<\/td><\/tr>
\"Bui

Bui Thi Linh<\/strong>
\u78a9\u58eb\u751f<\/strong><\/p><\/td>

\u5b78\u6b77\uff1a<\/strong>
Bs., Department of biotechnology and food technology, Thai Nguyen University of Agriculture and Forestry, Vietnam

\u7814\u7a76\u9818\u57df<\/strong>\uff1a
Characterizing probiotics with antimicrobial and bile salt hydrolase (BSH) activity for product development

\u7814\u7a76\u767c\u8868\uff1a<\/strong>
<\/td><\/tr>
\"Alonso

Alonso Enrique Africa<\/strong>
\u78a9\u58eb\u751f<\/strong><\/p><\/td>

\u5b78\u6b77\uff1a<\/strong>
Bs., College of Science of the University of Santo Tomas, Philippines

\u7814\u7a76\u9818\u57df<\/strong>\uff1a
Development and mechanism studies of antimicrobial active compounds
 
Development of compounds that inhibit PASTA kinase activity (side project)

\u7814\u7a76\u767c\u8868\uff1a<\/strong>
<\/td><\/tr>
\"\u5f35\u7d2b\u6797\u78a9\u58eb\u751f\"
\u5f35\u7d2b\u6797
\u78a9\u58eb\u751f<\/strong><\/td>		\u5b78\u6b77\uff1a<\/strong>
Bs., Department of Molecular Biology and Human Genetics, Tzu Chi University, Taiwan

\u7814\u7a76\u9818\u57df<\/strong>\uff1a
Characterization of novel virulence factors in H. pylori <\/em>pathogenesis

\u7814\u7a76\u767c\u8868\uff1a<\/strong>
<\/td><\/tr>
\"\u8b1d\u4f73\u7fbd\u78a9\u58eb\u751f\"

\u8b1d\u4f73\u7fbd<\/strong>
\u78a9\u58eb\u751f<\/strong><\/p><\/td>

\u5b78\u6b77\uff1a<\/strong>
Bs., Medical Laboratory Science and Biotechnology, China Medical University, Taiwan

\u7814\u7a76\u9818\u57df<\/strong>\uff1a
Antibiotic resistance

\u7814\u7a76\u767c\u8868\uff1a<\/strong>
<\/td><\/tr>
\"Laishram

Laishram Yashmine Devi<\/strong>
\u78a9\u58eb\u751f<\/strong><\/p><\/td>

\u5b78\u6b77\uff1a<\/strong>
Bs., Department of Biology, Indian Institute of Science Education and Research (IISER), India

\u7814\u7a76\u9818\u57df<\/strong>\uff1a
Next generation probiotics

\u7814\u7a76\u767c\u8868\uff1a<\/strong>
<\/td><\/tr>
\"Yi-Ru

Yi-Ru Boey<\/strong>
\u78a9\u58eb\u751f<\/strong><\/p><\/td>

\u5b78\u6b77\uff1a<\/strong>
Bs., Department of Life Science, National Cheng Kung University, Taiwan

\u7814\u7a76\u9818\u57df<\/strong>\uff1a
Recurrent infection

\u7814\u7a76\u767c\u8868\uff1a<\/strong>
<\/td><\/tr>
\"\u5433\u5bb9\u7444\u78a9\u58eb\u751f\"

\u5433\u5bb9\u7444<\/strong>
\u78a9\u58eb\u751f<\/strong><\/p><\/td>

\u5b78\u6b77\uff1a<\/strong>
Bs., Department of Food Science and Biotechnology, Chung Hsing University, Taiwan

\u7814\u7a76\u9818\u57df<\/strong>\uff1a
Development of probiotics

\u7814\u7a76\u767c\u8868\uff1a<\/strong>
<\/td><\/tr>
\"Nguyen

Nguyen Van Tat Thanh<\/strong>
\u78a9\u58eb\u751f<\/strong><\/p><\/td>

\u5b78\u6b77\uff1a<\/strong>
Bs.,  Pharmacological Medical and Agronomical Biotechnology at University of science and technology of Hanoi

\u7814\u7a76\u9818\u57df<\/strong>\uff1a
Development of probiotics

\u7814\u7a76\u767c\u8868\uff1a<\/strong>
<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

\u5433\u8389\u73b2\u8001\u5e2b\u5718\u968a<\/h4>\n\n\n\n
\"\u9ad8\u7fa9\u7b51(Yi-Chu

\u9ad8\u7fa9\u7b51(Yi-Chu Kao)
\u535a\u58eb\u751f<\/strong><\/strong><\/p><\/td>

\u5b78\u6b77\uff1a<\/strong>
M.D., Doctor of Medicine, Taipei Medical University, Taipei, Taiwan

\u7814\u7a76\u9818\u57df<\/strong>\uff1a
Pathophysiology of Liver, Ischemia and Reperfusion Injury of Liver,  Kupffer Cells and Innate Lymphoid Cells of Liver

\u7814\u7a76\u767c\u8868\uff1a<\/strong>
1. Hidenobu Kojima, Thomas A Morinelli, Yue Wang, Jackson L Chin, Aaron S Meyer, Yi-Chu Kao<\/strong>, Kentaro Kadono, Siyuan Yao, Taylor Torgerson, Kenneth J Dery, Adil Bhat, Elaine F Reed, Fady M Kaldas, Dirk J van der Windt, Douglas G Farmer, Jerzy W Kupiec-Weglinski, Yuan Zhai (2025, May). Group 1 innate lymphoid cells protect liver transplants from ischemia-reperfusion injury via an interferon gamma-mediated pathway. American Journal of Transplantation<\/em>, 25(5):969-984.

2. Chun-Han Lin, Ivy Yenwen Chau, Hao-Jan Lei, Shu-Cheng Chou, Yi-Chu Kao<\/strong>, Ching-Chu Chiang, Chan-Wei Tseng, Cheng-Yuan Hsia, Gar-Yang Chau (2025, Apr). Safety and Efficacy of the Hand-Assisted Laparoscopic Approach for Repeat Hepatectomy: A Propensity Score Matching Analysis. World Journal of Surgery<\/em>, 49(4):1090-1100.

3. Chen CE, Kao YC<\/strong>, Ku SH (2023, Oct). Fleur-de-lis Miniabdominoplasty Access in Radical Resection of a Large Abdominal Wall Desmoid Tumor. Plastic and Reconstructive Surgery – Global Open<\/em>, 26;11(10).

4. Lai HF, Chau IY, Lei HJ, Chou SC, Hsia CY, Kao YC<\/strong>, Chau GY (2022, Jan). Postoperative fever after liver resection: Incidence, risk factors, and characteristics associated with febrile infectious complication. PLOS ONE<\/em>, 13;17(1):e0262113. \u672c\u4eba\u70ba\u901a\u8a0a\u4f5c\u8005.

5. Lei HJ, Wang SY, Chau IY, Li AF, Chau YP, Hsia CY, Chou SC, Kao YC, Chau GY (2021, Jun). Hepatoma upregulated protein and Ki-67 expression in resectable hepatocellular carcinoma. Journal of the Chinese Medical Association<\/em>, 1;84(6):623-632.

6. Kao YC<\/strong>, Fang WL, Wang RF, Li AF, Yang MH, Wu CW, Shyr YM, Huang KH. (2019, Mar). Clinicopathological differences in signet ring cell adenocarcinoma between early and advanced gastric cancer. Gastric Cancer. Gastric Cancer<\/em>, 22:255-263. \u672c\u4eba\u70ba\u7b2c\u4e00\u4f5c\u8005.

7. \u9ad8\u7fa9\u7b51<\/strong>, \u5468\u66f8\u6b63, \u96f7\u6d69\u7136\uff082020\u5e7405\u6708\uff09\u3002\u6dfa\u8ac7\u975b\u6c30\u7da0ICG\u87a2\u5149\u986f\u5f71\u5728\u5fae\u5275\u809d\u81df\u624b\u8853\u7684\u61c9\u7528\u3002\uff0cPp. 255-259\u3002\u672c\u4eba\u70ba\u7b2c\u4e00\u4f5c\u8005\u3001\u901a\u8a0a\u4f5c\u8005\u3002<\/td><\/tr>
\"\u674e\u5ba5\u84c1\uff08You-jhen
\u674e\u5ba5\u84c1\uff08You-jhen Li \uff09
\u535a\u58eb\u751f<\/strong><\/td>		\u5b78\u6b77\uff1a<\/strong>
Institute of Biomedical Sciences, National Tsing Hua University, Hsinchu

\u7814\u7a76\u9818\u57df<\/strong>\uff1a
Gut microbiota, Obesity, Gut-Liver axis

\u7814\u7a76\u767c\u8868\uff1a<\/strong>
1. Po-Chun Huang, Jui-Chen Tsai, <\/strong>Kuan-Chen Chen, Ju-Yi Cheng, You-jhen Li<\/strong>, Ai-Leng Feng, Wei-Hao Peng and Li-Ling Wu. CRISPR\/Cas9-Mediated TLR4 Knockout Protects Male Mice from HFD-Induced Gut\u2013Liver\u2013Kidney Axis Dysfunction via Microbiota\u2013Immune Modulation. APCN & TSN 2025 . (Poster presentation) .<\/strong><\/td><\/tr>
\"\u8303\u6c9b\u6db5
\u8303\u6c9b\u6db5 (Pei-Han Fan)
\u78a9\u58eb\u751f<\/strong><\/td>		\u5b78\u6b77\uff1a<\/strong>
B.Sc Department of Microbiology, Immunology, and Biopharmaceuticals, National Chiayi University

\u7814\u7a76\u9818\u57df\uff1a<\/strong>
Gut microbiota, IBD, Gut barrier

\u7814\u7a76\u767c\u8868\uff1a<\/strong>
1. Jui-Chen Tsai, Kai-Hung Tsai, Ho-Yu Kuo, Pei-Han Fan<\/strong>, Hsiao-Li Chuang and Li-Ling Wu*<\/sup>. (2025) Protective Effects of Clostridium butyricum<\/em> on Gut Barrier Integrity and Intrahepatic Immune Response Against LPS-Induced Liver Injury. Digestive Disease Week\u00ae (DDW2025), San Diego, CA, U.S.A., 2025. (Poster presentation) (\u8ad6\u6587\u5091\u51fa\u6d77\u5831\u734e)<\/strong>

2. Kai-Hung Tsai, Jui-Chen Tsai, Ho-Yu Kuo, Pei-Han Fan<\/strong>, Wei-Hao Peng and Li-Ling Wu*<\/sup>\uff082025\uff09Integrated Multi-Omics Approach Reveals Nfil3<\/em>-Dependent Effects of Sleep Deprivation on Gut Barrier and Immune Surveillance in Hepatocellular Carcinoma. Digestive Disease Week\u00ae (DDW2025), San Diego, CA, U.S.A., 2025. (Oral presentation)<\/strong>

3. Kai-Hung Tsai, Jui-Chen Tsai, Ho-Yu Kuo, Pei-Han Fan<\/strong>, Wei-Hao Peng and Li-Ling Wu*<\/sup> \uff082025\uff09Multi-Omics Profiling Highlights Nfil3<\/em>-Driven Gut Barrier and Immune Dysregulation in HCC under Sleep Deprivation. APASL. 2025-3-26~30. Beijing, China.  (e-Poster presentation).<\/strong>

4. Jui-Chen Tsai, Kai-Hung Tsai, Ho-Yu Kuo, Pei-Han Fan<\/strong>, Hsiao-Li Chuang and Li-Ling Wu*<\/sup>. (2025) Clostridium butyricum-Derived Metabolites Enhance Gut-Liver Axis Integrity to Mitigate LPS-Induced Hepatic Inflammation. APASL. 2025-3-26~30. Beijing, China. (Poster presentation).<\/strong>

5. Chi-Chen Cheng, Hsiao-Ping Chen, Ho-Yu Kuo, Pei- Han Fan<\/strong>, Jie-Lun Ku, Cheng-Hao Kuo, Chun-Ying Wu, Li-Ling Wu* <\/sup>(2024). CRISPR\/Cas9-Mediated TLR4 Knockout Attenuates Hepatocellular Carcinoma Progression in Mice by Modulating the Kinetics of Myeloid-Derived Suppressor Cell Subsets. Taiwan Digestive Disease Week\u00ae (TDDW2024), Oct 5-6, 2024, Kaohsiun, Taiwan. (Poster presentation)<\/strong>

6. Chi-Chen Cheng, Hsiao-Ping Chen, Ho-Yu Kuo, Pei- Han Fan<\/strong>, Jie-Lun Ku, Cheng-Hao Kuo, Chun-Ying Wu, Li-Ling Wu*<\/sup>. CRISPR\/Cas9-Mediated TLR4 Knockout Attenuates Hepatocellular Carcinoma Progression in Mice by Modulating the Kinetics of Myeloid-Derived Suppressor Cell Subsets. Digestive Disease Week\u00ae (DDW2024), Washington DC. U.S.A., 2024. (Oral presentation)<\/strong>

7. Ho-Yu Kuo, Pei-Han Fan<\/strong>, Hsiao-Ping Chen, Chen-Hao Kuo, Kai-Hung Tsai, Jui-Chen Tsai, and Li-Ling Wu. Taurine-Mediated modulation of gut microbiota and inflammatory intrahepatic immune response attenuates fibrosis in CDAHFD-induced metabolic-associated steatohepatitis. Digestive Disease Week\u00ae (DDW2024), Washington DC. U.S.A., 2024. (Poster presentation)<\/strong> (\u8ad6\u6587\u5091\u51fa\u6d77\u5831\u734e)<\/strong>

8. Cheng-Hao Kuo, Hsiao-Ping Chen, Ho-Yu Kuo, Pei-Han Fan<\/strong>, Li-Ling Wu*<\/sup>, and Chun-Ying Wu*<\/sup>. METABOLIC SWITCHING, GUT INTEGRITY AND HOST-MICROBIOTA INTERACTION IN ALCOHOL-INDUCED INTESTINAL INJURY. Digestive Disease Week\u00ae (DDW2024), Washington DC. U.S.A., 2024. (Poster presentation)<\/strong>

9. Chia-Sheng Chu, Hsiao-Ping Chen, Pin-Hung Lin<\/strong>, Chi-Chen Cheng, Ho-Yu Kuo, Pei-Han Fan, Chun-Ying Wu and Li-Ling Wu*. ROLE OF IL-1R1 AND MYELOID-DERIVED SUPPRESSOR CELLS IN HEPATOCELLULAR CARCINOMA PROGRESSION AND IMMUNOTHERAPY. Digestive Disease Week\u00ae (DDW2024), Washington DC. U.S.A., 2024. (Poster presentation)<\/strong><\/td><\/tr>
\"\u8521\u93a7\u9d3b
\u8521\u93a7\u9d3b (Kai-Hung Tsai)
\u78a9\u58eb\u751f<\/strong><\/td>		\u5b78\u6b77\uff1a<\/strong>
B.Sc Department of Microbiology, Immunology, and Biopharmaceuticals, National Chiayi University

\u7814\u7a76\u9818\u57df\uff1a<\/strong>
Gut microbiota, HCC, Sleep deprivation

\u7814\u7a76\u767c\u8868\uff1a<\/strong>
1. Kai-Hung Tsai<\/strong>, Jui-Chen Tsai, Ho-Yu Kuo, Pei-Han Fan, Wei-Hao Peng and Li-Ling Wu*<\/sup>\uff082025\uff09Integrated Multi-Omics Approach Reveals Nfil3<\/em>-Dependent Effects of Sleep Deprivation on Gut Barrier and Immune Surveillance in Hepatocellular Carcinoma. Digestive Disease Week\u00ae (DDW2025), San Diego, CA, U.S.A., 2025. (Oral presentation)<\/strong>

2. Kai-Hung Tsai<\/strong>, Jui-Chen Tsai, Ho-Yu Kuo, Pei-Han Fan, Wei-Hao Peng and Li-Ling Wu*<\/sup> \uff082025\uff09Comprehensive Multi-Omics Analysis Identifies Mechanisms of Sleep Deprivation in Gut Microbiota and Immune Modulation of Hepatocellular Carcinoma in Nras\/Shp53\/SB100-Driven HCC mouse Models. \u7b2c39\u5c46\u751f\u7269\u91ab\u5b78\u806f\u5408\u5b78\u8853\u5e74\u6703, 2025. \u6a5f\u69cb:\u570b\u7acb\u967d\u660e\u5927\u5b78\u751f\u7406\u6240 (Poster presentation).<\/strong>

3. Jui-Chen Tsai, Kai-Hung Tsai<\/strong>, Ho-Yu Kuo, Pei-Han Fan, Hsiao-Li Chuang and Li-Ling Wu*<\/sup>. (2025) Protective Effects of Clostridium butyricum<\/em> on Gut Barrier Integrity and Intrahepatic Immune Response Against LPS-Induced Liver Injury. Digestive Disease Week\u00ae (DDW2025), San Diego, CA, U.S.A., 2025. (Poster presentation) (\u8ad6\u6587\u5091\u51fa\u6d77\u5831\u734e)<\/strong>

4. Ho-Yu Kuo, Pei-Han Fan, Hsiao-Ping Chen, Chen-Hao Kuo, Kai-Hung Tsai<\/strong>, Jui-Chen Tsai, and Li-Ling Wu. Taurine-Mediated modulation of gut microbiota and inflammatory intrahepatic immune response attenuates fibrosis in CDAHFD-induced metabolic-associated steatohepatitis. Digestive Disease Week\u00ae (DDW2024), Washington DC. U.S.A., 2024. (Poster presentation)<\/strong> (\u8ad6\u6587\u5091\u51fa\u6d77\u5831\u734e)<\/strong><\/td><\/tr>
\"\u8521\u777f\u8fb0
\u8521\u777f\u8fb0 (Jui-Chen Tsai)
\u78a9\u58eb\u751f<\/strong><\/td>		\u5b78\u6b77\uff1a<\/strong>
B.Sc <\/strong>Fu Jen Catholic University Department of Nutritional Science

\u7814\u7a76\u9818\u57df<\/strong>\uff1a
Gut microbiota, LPS, Gut Barrier function

\u7814\u7a76\u767c\u8868\uff1a<\/strong>
1. Jui-Chen Tsai<\/strong>, Kai-Hung Tsai, Ho-Yu Kuo, Pei-Han Fan, Hsiao-Li Chuang and Li-Ling Wu*<\/sup>. (2025) Protective Effects of Clostridium butyricum<\/em> on Gut Barrier Integrity and Intrahepatic Immune Response Against LPS-Induced Liver Injury. Digestive Disease Week\u00ae (DDW2025), San Diego, CA, U.S.A., 2025. (Poster presentation) (\u8ad6\u6587\u5091\u51fa\u6d77\u5831\u734e)<\/strong>

2. Jui-Chen Tsai<\/strong>, Kai-Hung Tsai, Ho-Yu Kuo, Pei-Han Fan, Hsiao-Li Chuang and Li-Ling Wu*<\/sup><\/strong>. (2025) Clostridium butyricum-Derived Metabolites Enhance Gut-Liver Axis Integrity to Mitigate LPS-Induced Hepatic Inflammation. APASL. 2025-3-26~30. Beijing, China. (Poster presentation).<\/strong>

3. Kai-Hung Tsai, Jui-Chen Tsai<\/strong>, Ho-Yu Kuo, Pei-Han Fan, Wei-Hao Peng and Li-Ling Wu*<\/sup> \uff082025\uff09Multi-Omics Profiling Highlights Nfil3<\/em>-Driven Gut Barrier and Immune Dysregulation in HCC under Sleep Deprivation. APASL. 2025-3-26~30. Beijing, China. (e-Poster presentation).<\/strong>

4. Kai-Hung Tsai, Jui-Chen Tsai<\/strong>, Ho-Yu Kuo, Pei-Han Fan, Wei-Hao Peng and Li-Ling Wu*<\/sup>\uff082025\uff09Integrated Multi-Omics Approach Reveals Nfil3<\/em>-Dependent Effects of Sleep Deprivation on Gut Barrier and Immune Surveillance in Hepatocellular Carcinoma. Digestive Disease Week\u00ae (DDW2025), San Diego, CA, U.S.A., 2025. (Oral presentation)<\/strong>

5. Ju-Yi Cheng, Jui-Chen Tsai<\/strong>, Po-Chun Huang, Pei-Hsuan Wu, Kai-Hung Tsai, Wei-Hao Peng*, and Li-Ling Wu*<\/sup>. (2025) <\/sup>CRISPR\/Cas9-Mediated TLR4 Knockout Reveals in Modulating Gut Microbiota and Metabolic Pathways under HBV-Induced Hepatocellular Carcinoma. Digestive Disease Week\u00ae (DDW2025), San Diego, CA, U.S.A., 2025. (Poster presentation) (\u8ad6\u6587\u5091\u51fa\u6d77\u5831\u734e)<\/strong>

6. Po-Chun Huang, Jui-Chen Tsai<\/strong>, <\/strong>Kuan-Chen Chen, Ju-Yi Cheng, You-jhen Li, Kai-Hung Tsai, Ai-Leng Feng, Wei-Hao Peng and Li-Ling Wu. CRISPR\/Cas9-Mediated TLR4 Knockout Protects Male Mice from HFD-Induced Gut\u2013Liver\u2013Kidney Axis Dysfunction via Microbiota\u2013Immune Modulation. APCN & TSN 2025 . (Poster presentation) .<\/strong>

7. Pei-Han Fan, Ho-Yu Kuo, Hsiao-Ping Chen, Kai-Hung Tsai, Jui-Chen Tsai<\/strong>, and Li-Ling Wu* BETAINE ALLEVIATES GUT BARRIER INFLAMMATION AND Ly6C MONOCYTES AND KUPFFER CELLS ORCHESTRATE LIVER IMMUNE RESPONES PREVENTS DSS INDUCED COLITIS AND ASSOCIATED LIVER INJURY. Digestive Disease Week\u00ae (DDW2024), Washington DC. U.S.A., 2024. (Poster presentation)<\/strong><\/td><\/tr>
\"\u5289\u5ba5\u7fbd
\u5289\u5ba5\u7fbd \uff08yo-yu Liou \uff09
\u78a9\u58eb\u751f<\/strong><\/td>		\u5b78\u6b77\uff1a <\/strong>Institute of Ecology and Evolutionary Biology, National Taiwan University

\u7814\u7a76\u9818\u57df<\/strong>\uff1aGut microbiota, HBV, Gut-Liver axis

\u7814\u7a76\u767c\u8868\uff1a<\/strong>
1. Yo-Yu Liou<\/strong>, Hurng-Yi Wang, Li-Ling Wu. Exploring the role of gut microbiota in HBV clearance in a transfected mouse model. NTU College of Life Sciences 113th Academic Year Science Poster Exhibition 2025. (Poster presentation) (\u7b2c\u4e00\u540d)<\/strong> .<\/td><\/tr>
\"\u8521\u67cf\u9716
\u8521\u67cf\u9716 (Po-Lin Tsai)
\u78a9\u58eb\u751f<\/strong><\/td>		\u5b78\u6b77\uff1a<\/strong>
B.Sc. Department of Nutrition and Health Science and Department of Nursing

\u7814\u7a76\u9818\u57df<\/strong>\uff1a
Gut microbiota, HCC, Sleep deprivation

\u7814\u7a76\u767c\u8868\uff1a<\/strong><\/td><\/tr>
\"\u65b9\u7fca\u665f\uff08Fang,
\u65b9\u7fca\u665f\uff08Fang, Yi-Cheng\uff09
\u78a9\u58eb\u751f<\/strong><\/td>		\u5b78\u6b77\uff1a<\/strong>
B.Sc Bioscience technology, Chung Yuan Christian University.

\u7814\u7a76\u9818\u57df<\/strong>\uff1a
Gut microbiota, Pathophysiology of Liver, Ischemia and Reperfusion Injury of Liver,  Kupffer Cells and Innate Lymphoid Cells of Liver

\u7814\u7a76\u767c\u8868\uff1a<\/strong><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n